Liverpool's defence of a Premier League crown won at a canter last season has become a nightmare
Danny Ings gave Southampton a surprise 1-0 home win over Premier League leaders Liverpool.
Beyond the handball incident, the Belgian champions were the better side on the night. Villa's World Cup-winning keeper Martinez was pressed into action early by Brugge, who had seven shots on target to the Premier League club's one, and made several key saves to keep his team in the game.
A summary of Wednesday's Champions League Round of 16, Second Leg, matches.
Victor Boniface rattled the post with a powerful shot eight minutes after the restart as Leverkusen picked up where they had left off.
A round-up of the UEFA Champions League last-16 first leg matches played on Tuesday.
A round-up of Saturday's action in the Premier League.
Rennes denied late Europa League equaliser due to little-known rule
European champions Liverpool made an emphatic start to the new Premier League season by scoring three times in the opening half an hour as they taught promoted Norwich City a harsh lesson with a 4-1 thrashing at Anfield on Friday.
Liverpool's 2-0 victory at Cardiff City on Sunday restored their two-point lead over champions Manchester City, who have played a game less.
Liverpool and Manchester City having the potential to "dominate" European football, former Scotland international Graeme Souness has said.
IMAGES from the English Premier League matches played on Saturday.
Liverpool won an absorbing English FA Cup final on Saturday as they prevailed 6-5 in a penalty shootout after the Wembley showpiece somehow ended 0-0 after extra time.
Basle FC lead online mocking of Liverpool.
Qualifying Newcastle United for the Champions League was not even in Eddie Howe's thoughts at the start of the season
Jude Bellingham topped the men's overall voting, with the Real Madrid and England midfielder receiving 11,176 selections from his peers.
Images from Saturday's action in the Premier League.
Images from Champions League matches played across Europe on Tuesday
A round-up of Wednesday's action in the UEFA Champions League.
Thiago, 29, won the Bundesliga title in each of his seven seasons with Bayern and played in last month's Champions League final victory over Paris St Germain.
Images from the English Premier League matches played on Sunday night.
The win moved Liverpool level with City on 86 points in the standings
A summary of Saturday's matches in the Premier League.
Forest's tally is the same number as Leicester City had accumulated by the same point of the 2015/16 campaign when they went on to become shock Premier League champions.
Ruud van Nistelrooy will take over on an interim basis.
Champions Liverpool suffered a shock 1-0 defeat to lowly Burnley on Thursday, ending their 68 match unbeaten home record in the Premier League as their title defence continued to fade.
A first-half penalty earned Lille a shock 1-0 home victory over holders Real Madrid in the Champions League group phase on Wednesday.
Edge Southampton 2-1 to take campaign to final day of the season.
Manchester City made sure of third place in the Premier League when they romped to a 5-0 win at Watford on Sunday to ensure a Champions League berth for next season.
Another Liverpool great, Graeme Souness, said Klopp had produced a "fabulous" side.
Aguero's absence means a likely start for Brazilian Gabriel Jesus in attack.
Vinicius Jr's remarkable performances at Real Madrid have put the 24-year-old forward as the odds-on favourite to claim his first Ballon d'Or when the award for the best player in the world is announced in Paris on Monday.
Liverpool stuttered into the quarter-finals of the Champions League with a 2-1 aggregate win over Inter Milan after suffering a 1-0 loss to the Italian side, who were reduced to 10 men, at Anfield on Tuesday.
Juventus were given a chance to avenge last year's Champions League final defeat by Real Madrid when they two sides were drawn together for the quarter-finals of this year's competition on Friday.
English champions and runners-up since the league restarted in the 1946-47 season after World War Two:
The first leg, originally scheduled to be held at the Red Bull Arena in Germany, was shifted to Budapest after German authorities denied Liverpool entry into the country due to COVID-19 protocols.
An 87th-minute header from defender Diego Llorente gave Leeds United a 1-1 home draw with Liverpool in the Premier League on Monday after the home side staged a protest against the breakaway Super League prior to the kickoff.
A summary of Sunday's action in the Premier League.
Images from Saturday's action in the Premier League.
Manchester City needed a second-half penalty from striker Erling Haaland to break the resistance of a dogged Crystal Palace.